Overview
Cyperus, a common perennial weed with tubers, is mainly used for digestive disorders. It is an anti-emetic
(suppresses vomiting); useful in reducing the symptoms of morning sickness during pregnancy because it gives the body a general
feeling of warmth.
Cyperus is sometimes used as a sedative, generally in connection with suppressing nausea.
It is also used to relieve gas in the stomach and intestines. In Amazonia, the indigenous people use it to treat infection and in
Africa it is used to treat epilepsy.
The properties of Cyperus (Purple nutsedge) are: analgesic, anthelmintic, antibacterial, antifungal, antispasmodic,
astringent, carminative, emmenagogue, hypotensive, sedative and is used as a tonic.
It is also used for the liver, menstrual disorders, menstrual pain, as a natural digestive stimulant and for memory.
To treat diarrhea, gas and infertility. It can help with some kinds of cervical cancer.
The calming effect of this plant helps relieve depression.
Phytochemicals
1,8-cineole, 4alpha,5alpha-oxidoeudesm-11-en-3-alpha-ol, Alkaloids, Alpha-cyperone, Alpha-rotunol, Beta-cyperone, Beta-pinene, Beta-rotunol,
Beta-selinene, Calcium, Camphene, Copaene, Cyperene, Cyperenone, Cyperol, Cyperolone Cyperotundone D-copadiene, D-epoxyguaiene, D-fructose, D-glucose,
Eo, Flavonoids, Gamma-cymene, Isocyperol, Isokobusone, Kobusone, Limonene, Linoleic-acid, Linolenic-acid, Magnesium, Manganese, Mustakone,
Myristic-acid, Oleanolic-acid, Oleanolic-acid-3-o-neohesperidoside, Oleic-acid, P-cymol, Patchoulenone, Pectin, Polyphenols, Rotundene, Rotundenol,
Rotundone, Selinatriene, Sitosterol, Stearic-acid, Sugeonol, Sugetriol
Pharmacology
Anticariogenic properties of the extract of Cyperus rotundus, research suggests
that Cyperus rotundus may inhibit cariogenic properties of Streptococcus mutans. Further studies are
necessary to clarify the active constituents responsible for such biomolecular activities.
A study was aimed to evaluate the wound healing activity of extract of tuber parts of Cyperus rotundus.
An alcoholic extract (herbal tincture) of tuber parts was examined for wound healing activity. The
wound healing property appears to be due to the presence of its active principles, which accelerates the healing process and
confers breaking strength to the healed wound. It is possible to conclude that the ointment of the extract of Cyperus
has significant wound healing activity at all the doses tested. It is comparable to those of the standard drug
Nitrofurazone ointment (0.2% w/w NFZ) in terms of wound contracting ability, wound closure time and tensile
strength.
Nitrofurazone (Furacin) is used to treat burns that have become infected. It is also used to treat
skin infections due to skin grafts. It works by killing bacteria or preventing their growth.
The crude extract of Cyperus rotundus was used for anti-inflammatory activity. The test exhibited a decrease
in hind paw volume at the dose 300 and 500 mg/kg administered orally. Significant dose dependent effect was
observed at higher dose but it was lesser than aspirin as standard drug on comparison. It was also observed
that maximum anti-inflammatory effect started after 1 hour and then started to decrease after 4 hours of
administration.
Muscle relaxation automatically decreased exploratory behavior by producing sedation. All hypotensives are
sedative to some extent. C. rotundus is also a natural hypotensive drug. This drug showing
slight effect on muscle relaxant activity as traction observed by control and C. rolundus extract treated
mice showed no significant difference of traction time among control and Cyperus treated animals. The relaxing
and sedative effect did not prolong the struggling time as compared to the control animal while antidepressant
drug having capability to prolong the struggling time on the basis of present finding it may be suggested
that Cyperus may act as relaxant, sedative and hypnotic but it may not be antidepressant. It is also
correlated with other behavioral tests like exploration, cage crossing, open field etc. Cyperus rotundus
is a tropical herbal medicine and in India is used traditionally for strengthening memory.
Dosage
Tincture: 2 - 3 ml daily (2 - 3 full pipettes)
Infusion (herbal tea): 1 - 2 cups daily
Reference
Inhibitory effects of methanol extract of Cyperus rotundus rhizomes on nitric oxide and superoxide productions by murine macrophage cell line, RAW 264.7 cells.
Seo WG, Pae HO, Oh GS, Chai KY, Kwon TO, Yun YG, Kim NY, Chung HT.
Department of Microbiology, Wonkwang University School of Medicine, Iksan, 570-749, Chonbuk, South Korea.
Wound healing activity of cyperus rotundus linn.
A Puratchikody¹, C Nithya Devi1¹, G Nagalakshmi²
¹ Department of Pharmacy, School of Engineering and Technology, Bharathidasan University, Tiruchirappalli-620 024, India
² Department of Pharmaceutical Chemistry, The Erode College of Pharmacy, Erode-638 112, India
Pharmacological studies on traditional medicine (Cyperus rotundus) used in Pakistan.
ASIF BIN REHMAN Institute/University/Department Details;
Department of Pharmacology/ University of Karachi Session, 2007 Subject Pharmacology.
The above presentation is for informational and educational purposes only.
It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage.
For many of the conditions discussed, treatment with prescribed (RX) or over - the - counter medication (OTC) is also
available.
Consult your doctor, practitioner, and/or pharmacist for any health problem and before using dietary supplements or
before making any changes in prescribed medications.
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